Virtual Dental

The cloud based application
targeted to clinical dental research

Multimodal 3D

Reimagining and shaping the future


For Tissue Recognition

Virtual Dental


Image Fusion

and Tissue Recognition


Collaborate with us

VDL - Virtual Dental Laboratory

Virtual Dental Laboratory is a Software package designed to obtain quantitative information on dental treatment through analysis of images obtained using tomographic techniques. The suite VDL is available as a web application, i.e., users can upload their image data and analyses them taking advantage of the power of cloud computing. VDL is able to detect differences between the 3D tooth structure as imaged before and after any treatment.
As an example, the buoyancy of an endodontic treatment can be evaluated through calculation of untreated surface and estimation of the volume of dentin removed, the percentage of treated canal surface treated and changes of radical channel axis in 3D space. The analysis is carried out quantitatively by dividing the root canal into three sections starting from the apex to the crown, or for every millimeter along the axis of the canal. For different treatments is possible to quantify the volume of voids embedded in the tooth structure, e.g., at the interface between a filling restorative material and the native tooth or
the appearance of internal cracks or it is possible to determine other morphological changes in tooth structure caused by tooth preparation or instrumentation.

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Image Fusion & Tissue Recognition

We developed an optimized pipeline combining Magnetic Resonance and X-ray Computed Tomography images in order to fuse images in a new 3D metastructure enhancing detection and identification of different tissue types embedded in the sample concerned. The Image Fusion can be applied to different tissues, organs and materials. This method is especially well suited for the analysis or the follow-up of biomaterial degradation and/or bone regeneration process, quantitative assessment of bone inflammatory processes and consequent bone weakness and degeneration.
As shown in the following example, MRI and X-ray images have different contrast because of the presence of more tissues imaged similarly by X-ray.
More generally, the fused structure can enhance information as obtained separately by different 3D and 2D imaging modality of every anatomical locations.

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Last Publication

Multimodal-3D imaging based on MRI and CT bridges the gap with histology in visualization of bone regeneration process

Journal of Tissue Engineering and Regenerative Medicine - R. Sinibaldi, A. Conti, B. Sinjari, G. Tromba, S. Capuani, T. Traini, S. Caputi and S. Della Penna


Analysis of cracks generated or modified by a dental treatment

Micro-CT allows studying the presence of cracks within the dentin and verifying whether these have originated

In this tutorial is analyzed the formation and propagation of micro cracks generated by endodontic treatment. . The endodontic treatment was applied two times consecutively on the same tooth to compare the effects of minimally invasive approach.


Department Maxillo Facial Sciences
Department of Physics

Department of Pharmacy
Department of Neurosciences

Elettra​ ​Sincrotrone Trieste​

Department of Environment
and Life Science

Institute for Complex System – CNR, Roma

Lintes – Research Laboratory ​

Italian Institute of Health (ISS)

Art & Science Magazine